{"id":276,"date":"2025-02-11T13:27:28","date_gmt":"2025-02-11T13:27:28","guid":{"rendered":"https:\/\/vingnanam.jfn.ac.lk\/?p=276"},"modified":"2025-02-12T13:34:34","modified_gmt":"2025-02-12T13:34:34","slug":"a-preliminary-study-on-the-toxic-effects-of-an-emerging-detergent-prinso-on-rat-skin","status":"publish","type":"post","link":"https:\/\/vingnanam.jfn.ac.lk\/?p=276","title":{"rendered":"A preliminary study on the toxic effects of an emerging detergent (Prinso) on rat skin"},"content":{"rendered":"<h4>Authors<\/h4>\n<div>\n<div>PBIAK Dayasiri, EPS Chandana<\/div>\n<div><\/div>\n<\/div>\n<h4>Abstract<\/h4>\n<div>\n<p>Toxic effects of household detergents on human skin have been reported previously. Recently emerged detergent \u201cPRINSO\u201d is extensively gaining popularity in many areas of Sri Lanka. \u201cPRINSO\u201d is also sold under other trade names such as \u201cEver Light\u201d, \u201cVihanga\u201d and \u201cDiamond Light\u201d. The product contains 2 sachets, one containing pink crystals (potassium permanganate) and the other containing white crystals (oxalic acid). Several cases have been reported on deliberate intoxication of \u201cPRINSO\u201d in order to commit suicide. Nevertheless, effect of \u201cPRINSO\u201d exposure on mammalian skin has not been reported. These observations prompted us to study the effects of \u201cPRINSO\u201d exposure (short-term) on mammalian skin. Twenty eight rats were randomly selected. In all rats, 4 cm<sup>2<\/sup>\u00a0area of skin was shaved on dorsal area just behind the neck. Rats were randomly assigned into four groups in which each group consisted of seven rats. Each group was randomly assigned for the treatments of distilled water, \u201cPRINSO\u201d and other two detergents namely \u201cTIDE\u201d and \u201cSUNLIGHT\u201d. Each shaved skin patch of the rats was treated with 5 ml of respective detergent solutions. Lesions were appeared after two days in the subjects where \u201cPRINSO\u201d solution was applied. Lesions were completely cured after 12 to 20 days. There were no detectable lesions in the groups treated with distilled water, \u201cTIDE\u201d and \u201cSUNLIGHT\u201d. These data indicates the primary toxic effects of \u201cPRINSO\u201d exposure on rat skin. Therefore effects of \u201cPRINSO\u201d on human skin should be tested rigorously.<\/p>\n<\/div>\n<h4>Download<\/h4>\n<p id=\"9abmxfyas2g-d2h5hx2cd0b-jmqy6vx9hpa-mxxqdwvcfof\" class=\"dOmORn gluBBo jwcObW jweaqt iTTIjY\" tabindex=\"-1\"><a href=\"https:\/\/vingnanam.jfn.ac.lk\/wp-content\/uploads\/2025\/02\/10-1-3.pdf\">Article [PDF]<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Authors PBIAK Dayasiri, EPS Chandana Abstract Toxic effects of household detergents on human skin have been reported previously. Recently emerged detergent \u201cPRINSO\u201d is extensively gaining popularity in many areas of Sri Lanka. \u201cPRINSO\u201d is also sold under other trade names such as \u201cEver Light\u201d, \u201cVihanga\u201d and \u201cDiamond Light\u201d. The product contains 2 sachets, one containing [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[44],"tags":[60,64,63,61,62],"class_list":["post-276","post","type-post","status-publish","format-standard","hentry","category-10-1","tag-detergents-prinso","tag-eps-chandana","tag-pbiak-dayasiri","tag-rats","tag-skin-lesions"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=\/wp\/v2\/posts\/276","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=276"}],"version-history":[{"count":2,"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=\/wp\/v2\/posts\/276\/revisions"}],"predecessor-version":[{"id":378,"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=\/wp\/v2\/posts\/276\/revisions\/378"}],"wp:attachment":[{"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=276"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=276"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/vingnanam.jfn.ac.lk\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=276"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}